wort parliament: October 2012

Wednesday, October 31, 2012

Why Early Learning Matters in This Election

This piece, co-written by LEV Policy Analyst Tracy Sherman and LEV Early Learning Community Organizer April Ritter, originally appeared in ParentMap on October 25th, 2012.

We all know we should care about elections, and we?ve heard that this year is especially important for education. This election is important for education at all levels, but some of the most affected students will be our state?s youngest ? those younger than five.

The next governor and legislature will make big decisions about services that help our state?s littlest learners get ready for school and life. Programs like free preschool for low-income children and all-day kindergarten for all students are so impactful because 85 percent of a baby?s brain develops before age five ? and most of it before age three. Rich learning environments during these years, whether in preschools, childcare centers or a neighbor?s back yard, can make a huge difference in a child?s life.

Crystal Garvin, mother of three, knows first-hand the importance of these programs. Her family has worked hard to succeed, but last year, she had to quit her job in her field because her wage was not enough to pay for childcare. Fortunately, her children are able to qualify for the Early Childhood Education and Assistance Program (ECEAP), the state?s preschool program for low-income children, and they could attend preschool, despite the cost.

Research tells us that high-quality early learning is important for all children, but it has an even greater impact on low-income children who often face a number of risk factors and start kindergarten behind their peers. While it is possible for children to catch up to where they should be academically, it is hard.

Continue reading here.

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Source: http://www.educationvoters.org/2012/10/30/why-early-learning-matters-in-this-election/

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When You Think About About Constructing Your New Home, Then It ...

When you think about about constructing your new home, then it is also efficient to concentrate on the issues related to make the finishing of your home as the best 1. Like other finishing, like furniture and other issues it is also essential to focus on the finishing of the flooring. This is because the incorrect finishing of floors might result with the leakages and other climate damages in the future. In order to stay away from these things, it is much better for the homeowners and also the builders to consider about the finishing of flooring. Facts about floor finishing When you decide to go via the best and efficient finishing for the floors, then there are many things that you need to think about before start with the flooring. Issues that you need to maintain in your thoughts prior to getting via the flooring are as follows: Since these days there are various types of flooring techniques available, you can choose with the one based on your needs. If you prefer to get with the fashionable and modern look to your home then it is much better to go via the modern flooring finishes that are accessible and also you can go via the commercial one. If you believe of getting through the fashionable look to your home, then it will be much better to go via the traditional flooring techniques accessible When you believe about the flooring finishing, most of the individuals these days prefer with the wood flooring finishing rather than other people. Because of this cause, it is much better to verify out the high quality of wood prior to install that to your flooring and also you have to consider about the issues need for the objective of sharpening the wood. It is efficient to go through the specialists to make the flooring as the greatest one The primary factor that you need to consider is about the leading place finishing of the flooring. This can make the appearance of the flooring as efficient and dependable 1 If you think about about all these issues, then you will most likely make out the flooring of your house in an effective manner. Industrial flooring finishing When you believe about the floor finishing of industrial buildings instead than house, it is necessary to maintain some issues in mind concerning the powerful and also the high quality of the flooring. This is because the flooring has to be designed in this kind of a way to handle with all sorts of workloads and also in a durable manner. Since most of the individuals today favor to run more than the successful business enterprise, it is effective for them to have their personal buildings as the expert one. This is also regarded as as the essential need to attract the clients and also to have get in touch with with the people in a better way. It is also regarded as as the important one for the secure of workers and also the goods. If you want to get through much more info regarding the floor finishing, then it will be much better to go through the on-line web sites to get sufficient particulars.

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How Sandy turned into a superstorm

The combination of a winter-time jet stream, warm tropical air and a full moon is turning Sandy into a huge and complicated storm that has the potential to devastate the Northeast and parts of the Mid-Atlantic. TODAY's Matt Lauer reports.

By Alan Boyle

Hurricane Sandy is posing a monster challenge for weather forecasters and emergency agencies, due to an amazing combination of meteorological factors, but what's just as amazing is how well they've been able to predict what seemed to be an unpredictable disaster.

"It looks like we've been fairly consistent on this, even five days out," Chris Landsea, science and operations officer at the National Hurricane Center in Miami, told me today. "I think when all is said and done, on the track forecast, we're going to be quite accurate."

Sandy's path, which took a left turn from the Atlantic to slam head-on into the heavily populated Northeast, is just one of the unusual aspects of this storm. "The size of this system, the late-season nature, and the track?? all these are fairly unique characteristics," Landsea said. To look for precedents, you have to go back to infamous hurricanes such as Agnes in 1972, Hazel in 1954, even the great storms of 1944, 1938, 1815 and?1804. But today, the region is so much more populous and developed that the impact is certain to be far greater.

Here are five factors that have turned Sandy into a superstorm:

Northerly track: Atlantic tropical storms most commonly tear through the Caribbean and the Gulf of Mexico, and lose energy as they pass over the U.S mainland. This storm, however, crept along the Eastern Seaboard, where waters that were warmer than usual for this time of year kept the storm alive. As the storm moved northward, it morphed into a hybrid storm, drawing additional strength from the differential between the storm's warm air and cold northern air from the jet stream.

"There's a transformation that this system is undergoing," Landsea explained. "This is actually evolving into a winter storm, and later, a nor'easter." One result of this evolution is that the storm system has widened to more than 800 miles in diameter, stretching from the Carolinas to Maine and Canada.

NASA / NOAA

NOAA's GOES-13 weather satellite shows the storm system associated with Hurricane Sandy covering the northeastern United States even before landfall on Monday.

The left turn:?Hurricanes that get so far north could drift off into the cold Atlantic to die?? but they can also be pushed into the mainland, as Hurricane Irene was last year. Irene followed a path that was roughly parallel to the coastline, but Sandy took a hard left turn that put it on a course for a direct, perpendicular strike on the coast. That's because a cold front on the mainland is drawing the storm westward, while the current state of a weather pattern known as the North Atlantic Oscillation is blocking the storm from heading eastward.?

Storm surge: Sandy's top sustained winds of 85 miles per hour typically wouldn't rate as a superstorm, but its effects will be magnified, Landsea said. "Even though it's not a 'major' hurricane by any means ... there is substantial threat because of the storm surge and because of the rainfall. There's going to be flooding. Both of those factors are going to be killers," he said. The storm surge is projected to range from 6 to 11 feet. One of the big reasons for such a high surge is that the waters off the coast of New York and New Jersey are so shallow: As the surge from the deeper ocean nears the coastline, all that water piles up to create a higher wave.

Full moon:?Another reason for the huge storm surge is the fact that the moon is hitting its full phase just as Sandy is making landfall. The celestial lineup of the sun, moon and Earth contributes to higher-than-normal high tides.?

Winter storm: Sandy is such a late-season storm that it's running into winter weather in the northeastern United States, which is adding an extra dimension to the misery. "I have not been around long enough to see a hurricane forecast with a snow advisory in it," Craig Fugate, administrator of the Federal Emergency Management Agency, told NBC's TODAY. The storm could trigger up to 3 feet of snow in the Appalachians, the National Weather Service reported. The Weather Channel's Tom Niziol said that "an amazing combination of factors" have come together to make Sandy a threat due to the snow as well as the rain.

Landsea and other forecasters may marvel at the factors behind what some have called a "perfect storm" or "Frankenstorm," and there'll surely be lots of lessons learned for future weather modeling. But that's not what's uppermost on their mind right now. "What's really important are the impacts," Landsea said.

To keep on top of the storm, and to keep safe, keep an eye on NBC News' hurricane coverage:

Update for 3:10 p.m. ET Oct. 30:?The storm surge was clearly one of the biggest impacts of Hurricane Sandy, and for good reason: The National Hurricane Service reported that in some cases, the surge exceeded its own maximum prediction of 11 feet. At New York's Battery Park, for example, the surge measured 13.7 feet ? and it was devastating. On another note, I've corrected the spelling of Landsea's apt last name since this item was originally published.

Alan Boyle is NBCNews.com's science editor. Connect with the Cosmic Log community by "liking" the log's?Facebook page, following?@b0yle on Twitter?and adding the?Cosmic Log page?to your Google+ presence. To keep up with Cosmic Log as well as NBCNews.com's other stories about science and space, sign up for the Tech & Science newsletter, delivered to your email in-box. You can also check out?"The Case for Pluto,"?my book about the controversial dwarf planet and the search for new worlds.

Source: http://cosmiclog.nbcnews.com/_news/2012/10/29/14779057-how-sandy-turned-into-a-superstorm?lite

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Cassel to start at QB for Chiefs vs Chargers

KANSAS CITY, Mo. (AP) ? Matt Cassel is getting another chance to be the Chiefs' starting quarterback.

Cassel will start Thursday night's game at San Diego because Brady Quinn has not been cleared to practice due to a concussion, regaining the starting job ? at least for one week ? that he lost after a dismal five-game stretch to start the season.

Chiefs coach Romeo Crennel announced Tuesday that Quinn will not be available, and that Ricky Stanzi will serve as the backup. Fullback Nate Eachus was also ruled out with a concussion.

"They will continue with their testing and evaluation and will return when the doctor releases them, and lets us know they're OK," said Crennel, adding that doctors haven't told him how long Quinn might be out.

Cassel was scuffling along until he sustained his own concussion a few weeks ago against Baltimore. Quinn took over for a loss to Tampa Bay, and Crennel made the move permanent during the bye week in hopes of igniting a struggling offense.

He never got much chance to see whether it worked.

Quinn was hurt in the first quarter of Sunday's 26-16 loss to the Oakland Raiders, though it's unclear when the injury occurred. He was sacked by Rolando McClain and then took another shot while floating a pass that was picked off by Matt Giordano.

Quinn left the field and went down the tunnel leading to the locker rooms, and Crennel said a trainer told him at that point that Quinn had sustained a "head injury" and was unavailable.

Cassel played the rest of way, completing 20 of 30 passes for 218 yards with a touchdown and an interception. It was the 10th pick that he's thrown in parts of six games this season.

"I'm excited to be playing," Cassel said. "As I said last week, my approach doesn't change. I'm going to go out (and) I'm going to work hard. It's unfortunate for Brady, but at the same time, we have to move forward. It's a short week. Preparation has to be put in."

Cassel, who signed a $63 million, six-year deal in 2009, said he doesn't harbor any ill will toward Crennel over his benching. Cassel also said he doesn't find it uncomfortable that he's regained the starting job on a temporary basis almost by default.

"I don't look at it that way," Cassel said. "No matter what my position is, I'm going to be the same guy, and I think that's the reason I was able to go in there and execute at a high level Sunday. I was ready and my approach was the same."

Cassel said he wasn't sure whether coming off the bench changed his perspective, but his coach indicated that the decision may ultimately help Cassel from a mental standpoint.

"Sometimes a second chance energizes a guy," Crennel said. "He wants to do well, and whatever role he was in, he didn't like it, but he said, 'I'm going to do my job. I'm a Chief, and I'm going to be ready if I'm called on."

The Chiefs (1-6) could certainly use a little energy. They've lost four straight overall and still have not led in regulation this season, making them the first NFL team since at least 1940 to play seven games without taking an offensive snap with the lead, according to STATS LLC.

They've also turned the ball over a league-leading 25 times after four turnovers Sunday.

Cassel has responsible for two more on Sunday when he fumbled a snap early in the second half that led to a field goal by Oakland. He's committed 16 turnovers by himself, which puts him ahead of all but three teams in the league: Dallas, Buffalo and Philadelphia.

"He knows he's going to have to play, and he's going to do the best he can," Crennel said. "We have to help him as well, and if we all take the same attitude we'll be successful."

Offensive coordinator Brian Daboll said it helps, given the short week, that Cassel was the starter when the Chiefs played San Diego earlier this season. Cassel committed three turnovers in the game, but he'll be familiar with the Chargers' schemes and personnel.

"He's preparing himself like a pro to be ready to go in this football game," Daboll said. "He's got a good attitude, he's taken Brady being put ahead of him well. If you ask him, I'm sure he's anxious, excited for the opportunity."

___

Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL

Source: http://news.yahoo.com/cassel-start-qb-chiefs-vs-chargers-191157752--nfl.html

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'You can't resell that' ? A guide to today's Supreme Court copyright ...

Publishers and manufacturers want to use copyright to stop people selling books or watches from other countries in the US. The Supreme Court is hearing a major case today that will force it to choose between consumers and sellers.

Is this the end of the yard sales? News media are making a fuss about a court decision that lets publishers use copyright to prevent consumers from reselling imported goods.

Today, the Supreme Court will take a closer at this ?grey marketing? issue ? and decide how to balance consumers? right to use their property against owners? rights to set prices.

The outcome will affect your right to buy and sell books, music and more. Here?s a plain-English guide to what the case is about and what it means for you:

What do you mean I can?t resell this book? I bought it fair and square

In the past, a publisher?s right to control distribution ended after they sold a book ? copyright?s ?first sale? rule. But last year, an appeals court said this rule only applied if the book (or other item) was made in the US . This means that if you resell a book or a toy made in China or the UK, you?re infringing copyright.

What led to the ruling?

A Thai-born man studying at a US school realized he could buy his textbooks much cheaper in his home country. He began importing large quantities of books and reselling them on eBay. Other people began doing the same, leading publisher John Wiley to bring a copyright suit to stop this. Last year, an appeals court sided with John Wiley.

Does this apply to just books or to any imports?

It can apply to anything protected by copyright. The case is so important because manufacturers are relying on the rule, too ? by putting artistic designs on their products so they qualify for copyright protection. That?s what watch maker Omega did a few years ago; Omega put a tiny picture on its watches ?and then sued the retailer Costco for copyright infringement (Omega was upset that Costco was buying the watches overseas and then selling below the suggested price in the US).

Here?s a look at the tiny design that Omega used to make its watches eligible for copyright protection (other companies will likely try the same trick) :

In the bigger picture, the textbook and Omega watch cases show how real time information makes it easier for sellers to engage in arbitrage ? buying goods in other markets to resell back here. Publishers and manufacturers believe the resellers are engaged in an unfair business practice and are using copyright to stop this.

But what if I have a yard sale or sell my stuff on Craigslist?

That?s the problem. In the John Wiley textbook case, the appeals court didn?t set out any limits to the ?no resale? rule. This means, in theory, that anyone who resells an overseas good could be violating copyright.

In reality, it?s a pretty safe bet that publishers and manufacturers are not going to run around shutting down garage sales. But the ruling could spell trouble for used book stores, consignment stores or other merchants who sell used goods.

If you?re into the legal nitty-gritty, the Copyright Act has two sections that seem to contradict one another: One section says unauthorized imports violate a copyright owner?s exclusive right to distribution (which favors the publisher). The other section limits the rights of the copyright owner by saying the owner of a copy??lawfully made under this title? can sell it (which favors the consumer).

What?s the Supreme Court going to do?

The court can overturn the appeals court case, leaving us to carry on as before.?If it decides to uphold the ruling, the vourt may try to limit its effect, perhaps by declaring the rule only applies in special cases. Or it may simply uphold the case and leave it to Congress to clean up the ensuing resale mess.

How does the case affect digital book or music sales?

?
It won?t have a big affect because, for better or worse, we don?t really own our digital books and music ? we license them from Apple or Amazon. The Supreme Court case ? which turns on physical objects we do own ? is about non-digital property.

Any predictions on the outcome?

The Supreme Court heard the same issue in 2010 when Omega and Costco argued about the watches. That case resulted in a 4-4 tie which means the lower court ruling against Costco (and consumers) was upheld.?The tie came because Justice Elena Kagan recused herself. She will cast a vote this time ? likely the deciding one. It?s hard to predict which side she will take.

I can?t get enough of this first sale copyright stuff. Where can I learn more?

Legal reporter Joe Mullin of Ars Technica has a great profile of the facts and legal background:?How a Supreme Court ruling may stop you from selling just about anything. And SCOTUSblog has the filings and more for?Kirtsaeng v. John Wiley & Sons.

(Image by Monkey Business Images via Shutterstock)

Source: http://paidcontent.org/2012/10/29/you-cant-resell-that-a-guide-to-todays-supreme-court-copyright-case/

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Tuesday, October 30, 2012

Saucedo elementary special education - Chatham/Avalon Park ...

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Source: http://chathamavalonparkcommunitycouncil.blogspot.com/2012/10/saucedo-elementary-special-education.html

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San Francisco gets ready for Giants' parade

SAN FRANCISCO (AP) ? For the second time in three years, San Francisco is gearing up for a ticker-tape parade to celebrate a World Series victory for the Giants.

Plans for the Wednesday bash were being made as the city cleaned up after a rowdy celebration Sunday night turned violent in some neighborhoods and police arrested three dozen people.

"I'm not going to let the spirit of this city be destroyed by 36 people," Mayor Ed Lee said. "We're going to move forward with a great parade, a wonderful celebration."

The parade will take a slightly different route from the one that followed the Giants' 2010 championship. Instead of the financial district, it will start at the foot of Market Street.

The new route is safer and affords better views than the previous route, which followed a path taken in 1958 to introduce the Giants to San Francisco after their move from New York, Mayor's Office spokesman Francis Tsang said.

"A lot has changed since then," he added.

Regardless of the route, hundreds of thousands of fans are expected to turn out and rival the crowd that celebrated in 2010, when players, coaches and other luminaries rode in open-air buses designed to look like cable cars and vintage convertible cars.

Tens of thousands of people crowded into a park across the street from City Hall at the end of that parade to hear players, coaches and executives thank fans for their support.

This year, the parade occurs on Halloween, a historically notorious night for San Francisco, with landmarks such as Coit Tower and City Hall bathed in orange and black light.

In previous years, hundreds of thousands of revelers descended on the Castro neighborhood, and authorities struggled to control the crowds. After a shooting in 2006 wounded nine people, officials canceled the party and the night is now marked by a heavy police presence.

As some city workers were busy Monday erecting VIP stands in front of City Hall, others were sweeping up broken glass and charred debris left behind in the Mission District and other neighborhoods where the revelry turned violent after midnight.

The Police Department arrested 36 people, the majority in the Mission. Two were taken into custody on gun charges.

However, Sgt. Michael Andraychak said the vast majority of celebrations throughout the city, from the gay mecca of the Castro to touristy North Beach, were rowdy but peaceful. Fans doused each other with beer and champagne and danced in the streets, blocking motorists who happily honked their horns in celebration while stuck in gridlock.

"There were celebrations all over the city, and they were all peaceful and upbeat," Andraychak said. "Unfortunately, as the night progressed, this other element emerged and was intent on doing violence."

Bonfires of trash were lit in several intersections, and a $700,000 public transit bus was torched. Windows were broken out of several businesses and vehicles, including a news van.

Firefighters needed a police escort to douse a bonfire near the Giants' ball park. They also fought fires fueled by couches, news racks and other debris.

Police said a damage report was not yet available.

Police said most of the violence and damage occurred several hours after the last pitch and miles from Civic Center, where an estimated 10,000 peaceful fans watched the game on a giant Jumbotron television hastily erected by the city.

Mayor Lee said fans who watched the Giants endure six elimination games in the first two rounds of the playoffs before winning the World Series in four games "have a right to release that energy in a positive way."

Staff writer Terry Collins in San Francisco contributed to this report.

Source: http://news.yahoo.com/san-francisco-gets-ready-giants-parade-214531813--finance.html

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Hospitals should make flu shots mandatory for health-care workers ...

A new Canadian study suggests the flu vaccine significantly lowers the risk of heart attack, strokes and dying from heart disease.

Photograph by: Henry Romero, Reuters , Postmedia News

TORONTO ? The Canadian Medical Association Journal has added its voice to calls for mandatory flu shots for health-care workers.

In an editorial published in this week?s issue, the journal said hospital workers ought to be vaccinated to safeguard frail, elderly patients whose immune systems are so weakened they don?t get much protection from a flu shot themselves.

?We would like individual hospitals to think about taking the initiative,? said Dr. Ken Flegel, senior associate editor and a general internal medicine specialist at Montreal?s McGill University Health Centre.

Flegel acknowledged there will likely be pushback from health-care workers, the majority of whom do not get a flu shot.

?I don?t want anyone to make me do something I don?t believe in or I don?t agree to do to my body,? he said.

?I think that?s a sort of fundamental right. On the other hand, I think the hospital has to say ?That?s fine by us but don?t come near our patients because you?re a hazard to our patients.??

In recent years there has been a growing movement towards requiring health-care workers to take a flu shot, especially in the United States. Earlier this year British Columbia became the first Canadian jurisdiction to require health-care workers to be vaccinated against the flu.

The B.C. policy applies to hospital workers, staff of long-term care homes and community-based health-care workers. It does not cover doctors in private practice. Health-care workers who forgo a flu shot will have to wear a mask on the job from Dec. 1 to the end of March.

Dr. Perry Kendall, the province?s chief medical officer of health, said health-care worker vaccination rates ? which were never high ? have been dropping since 2007.

?If we really think it will make a difference, why do we keep on sitting on the fence and accepting declining levels? It either is important enough to really do it or it isn?t,? Kendall said.

Health-care unions, which had supported B.C.?s efforts to raise flu shot rates among members, were not happy about the new policy.

?They would rather it is a voluntary program and so would I, frankly. But that just hasn?t worked,? Kendall said.

The call to make flu shots mandatory comes at a time when serious questions are being asked about how effective flu vaccine actually is. And some of the studies the journal editorial cites in making its case are among those that have been called into question.

It suggests, for instance, that flu vaccine is about 86 per cent effective at preventing flu when the strains in the shot are well matched to circulating viruses. But the study cited as the source of that information doesn?t actually make that claim. Flegel said he got the number from another study, which credited the study Flegel cited.

A recent comprehensive review of influenza vaccine written by the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota said the scientific literature on flu vaccine is littered with mistakes ? studies that misconstrue what previous research has found or which have design flaws.

The result has been an over-estimation of how much protection current flu vaccines can offer, the CIDRAP report said.

In the last couple of years many expert groups have quietly toned down their language on flu shots, lowering the efficacy estimates to 50 to 70 per cent from the 70 to 90 per cent that was previously claimed.

(It should be noted the studies that assess efficacy are typically done in healthy adults, the people whose immune systems are most likely to respond well to a flu shot. That means those efficacy estimates are a best-case scenario.)

Michael Osterholm, senior author of the CIDRAP flu vaccine report, said public health officials need to be careful not to over sell flu vaccine.

?I fully support the vaccination of health-care workers. But we must be held to a standard of science that we expect anyone who opposes vaccination to also be held to,? he said.

Flegel acknowledged that may be a problem. ?We probably have been too enthusiastic about the protection rate available from the flu vaccine,? he said after learning of the problem in his citations.

But he said even if the vaccine offers only 50 per cent protection, minimizing the risk that health-care workers sick with the flu will pass it to their vulnerable patients makes sense.

The fact that the vaccine doesn?t work as well as people would like can actually be used as an argument for requiring health-care workers to get flu shots, said Dr. Kumanan Wilson, a Canada Research Chair in health policy at the Ottawa Hospital Research Institute.

Wilson, who researches vaccine acceptance issues, recently co-wrote an article exploring the issue of mandatory influenza vaccination for health-care workers in the publication Health Law Journal.

?The fact that the vaccine is not so good actually necessitates a high percentage of health-care workers getting the vaccine in order to create some level of herd immunity,? Wilson said in an interview.

?So as long as it has some effectiveness, a reasonable level of effectiveness, you could use that as an argument ?This is why we have to mandate everybody get it.??

Still, Wilson said requiring workers to take a flu shot isn?t something hospitals or governments should do lightly. ?Because people will perceive it as a major infringement on their liberty. It?s actually putting a needle into someone. So you really need to be careful how you proceed with this.?

Wilson said mandatory flu shot programs should include commitments from the authorities making the policy that they?ll review emerging scientific data on the safety and efficacy of flu vaccine on an ongoing basis.

As well, he said, authorities should commit to studying whether the program is actually working. They should also monitor for any vaccine-induced side-effects and commit to compensate any health-care worker who sustains a health injury that can be linked back to the flu shot.

?If you do bring it in, you have to do it respectfully and showing that you understand the concerns of health-care workers,? said Wilson, who noted that he supports the idea of vaccinating health-care workers against influenza.

?If you don?t do that, then it comes across, I think, as a bit heavy handed.?

? Copyright (c) The Calgary Herald

Source: http://www.calgaryherald.com/entertainment/Hospitals+should+make+shots+mandatory+health+care+workers/7465314/story.html

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Harriet Cabelly: Don't Let the Friendship Boil Over -- Talk It Out

I'm trying to soothe my soul. It's been deeply hurt. I've also inflicted tremendous hurt on a person whose response in a Dear John email is that we are no longer friends and I am not to reach out to her again. She has cut off our 40-year friendship like a branch snapped off from a tree.

Actually, we met some 45 years ago in school and were close friends for about seven years. She then moved to the other side of the world, and we were in touch periodically, and then about seven years ago we reestablished ties and resumed a very close relationship.

I am one to look at my part, at my responsibility. I make no excuses; I did her a terrible injustice. She published a book and presented me with one of the first copies, and I did not read it. It's been more than a year since I've had it, and it still sits on my night table unread. I had told her I would read it in the summer, as I had many books to read for my five book clubs I was leading at work last year. But no, I still didn't "get to it."

After reaching out to her a few times via phone and email, as I was going to Israel to visit my daughter and family and wanted to make plans to spend time together, as we always do, I got no response. I reached out one more time and finally got what I wished for: a response back with an explanation. But what I certainly did not wish for was the shocking final statement, that we've come to the end of our relationship.

No space left for apology, discussion, argument. A cold turkey ending. Whew, this hurts. This will obviously sit with me for a long time, this sadness, this loss. The loss of someone who knows me so well: the history, the future travel plans, the laughter, the appreciation and gift of a friendship reignited -- all gone so suddenly.

I am guilty of causing a dear friend pain by not making time for her most meaningful and important accomplishment. I hurt her to the core. I accept complete responsibility. No excuses; I am wrong.

There were some other itemized points of wrongdoing on my part, but this was the last and most comprehensive -- the one that cut to the core.

I am a straight shooter and prefer to be told straight on what the problem is. I don't like BS, and I'd rather hear the truth, even if it hurts, than some nonsense excuse. I like to know where I stand. I certainly heard the truth, but the sudden death of our long-term relationship has me shaken and reeling.

I want to offer this: We all let things go, small hurts or injustices to one another. We don't want to bring up every little thing. We look away in our attempts to be benevolent, knowing we all have flaws and limitations.

But when something is brewing and starts to get in the way of feeling good in a relationship, or resentment starts to build, that's the time to speak up and air the problem. It's obviously not a place we necessarily want to go -- to bring up a discomfort or bad feeling -- but it beats the alternative of having something blow up in one's face and end up with nothing at all.

If something is starting to bubble up inside and the relationship is important to you, bring it up. Talk about it, argue about it, do something about it. But don't let it die. Relationships are what life is all about.

Relationships are easy when everything is sailing along smoothly. The real test is when trouble sets in, when misunderstandings occur, when wrongdoings occur, when mistakes are made, when hurts are inflicted. How do we handle it? What do we do with those difficult feelings? We can't be mind readers and we don't always know how our actions and words affect another person. We need to be open to telling and open to receiving. That's what makes for the authentic, meaningful and deep connections.

So please go out and tell your friend/important person what's bugging you, if it's a relationship you want to preserve. You might be surprised; it can bring in a whole new level of connection. When we're able to grow in healing, we grow in closeness.

For more by Harriet Cabelly, click here.

For more on relationships, click here.

Follow Harriet Cabelly on Twitter: www.twitter.com/Rebuild Life

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Source: http://www.huffingtonpost.com/harriet-cabelly/friendship-advice_b_2013345.html

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The 31 scariest Superstars

All WWE programming, talent names, images, likenesses, slogans, wrestling moves, trademarks, logos and copyrights are the exclusive property of WWE, Inc. and its subsidiaries. All other trademarks, logos and copyrights are the property of their respective owners. ? 2012 WWE, Inc. All Rights Reserved. This website is based in the United States. By submitting personal information to this website you consent to your information being maintained in the U.S., subject to applicable U.S. laws. U.S. law may be different than the law of your home country. WrestleMania XXIX (NY/NJ) logo TM & ? 2012 WWE. All Rights Reserved. The Empire State Building design is a registered trademark and used with permission by ESBC.

Source: http://www.wwe.com/classics/classic-lists/31-scariest-superstars

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Photos: NYC a ghost town as storm approaches

A view shows the Holland Tunnel before being shutdown for weather conditions while Hurricane Sandy approaches to New Jersey, October 29, 2012. Hurricane Sandy, the monster storm bearing down on the U.S. East Coast, strengthened on Monday after hundreds of thousands moved to higher ground, public transport shut down and the U.S. stock market suffered its first weather-related closure in 27 years. REUTERS/Eduardo Munoz (UNITED STATES - Tags: ... more?A view shows the Holland Tunnel before being shutdown for weather conditions while Hurricane Sandy approaches to New Jersey, October 29, 2012. Hurricane Sandy, the monster storm bearing down on the U.S. East Coast, strengthened on Monday after hundreds of thousands moved to higher ground, public transport shut down and the U.S. stock market suffered its first weather-related closure in 27 years. REUTERS/Eduardo Munoz (UNITED STATES - Tags: ENVIRONMENT DISASTER) less?

Source: http://news.yahoo.com/photos/nyc-empties-ahead-of-hurricane-sandy-slideshow/

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Never mind the bollocks (Powerlineblog)

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Giants blow 23-point lead, but win 29-24 at Dallas

Dallas Cowboys tight end Jason Witten (82) is tackled by New York Giants outside linebacker Michael Boley (59) and Keith Rivers (55) during the first half of an NFL football game, Sunday, Oct. 28, 2012, in Arlington, Texas. (AP Photo/Tony Gutierrez)

New York Giants defensive end Jason Pierre-Paul (90) celebrates with Stevie Brown (27) after intercepting a pass from Dallas Cowboys quarterback Tony Romo and returning it for a touchdown during the first half of an NFL football game, Sunday, Oct. 28, 2012, in Arlington, Texas. (AP Photo/Sharon Ellman)

Dallas Cowboys wide receiver Dez Bryant (88) makes a last-minute reception between New York Giants cornerbacks Corey Webster (23) and Michael Coe (37) for a touchdown that was nullified after review during an NFL football game, Sunday, Oct. 28, 2012, in Arlington, Texas. Bryant's hand landed on the line. The Giants won 29-24. (AP Photo/Sharon Ellman)

Dallas Cowboys quarterback Tony Romo (9) gets past New York Giants middle linebacker Chase Blackburn (93) to score a touchdwon during the second half of an NFL football game Sunday, Oct. 28, 2012 in Arlington, Texas. (AP Photo/Sharon Ellman)

Dallas Cowboys wide receiver Dez Bryant (88) is taken down by New York Giants cornerback Jayron Hosley (28) and Stevie Brown (27) during the first half of an NFL football game Sunday, Oct. 28, 2012 in Arlington, Texas. (AP Photo/Sharon Ellman)

ARLINGTON, Texas (AP) ? Eli Manning stood on the New York Giants' sideline in disbelief when it looked as if the Dallas Cowboys had scored a go-ahead touchdown with 10 seconds left.

What was encouraging is what he didn't see: a replay on the giant videoboard that hangs above the field at Cowboys Stadium, where the Giants still have never lost following a wild 29-24 victory Sunday.

Officials reviewed and overturned Dez Bryant's apparent 37-yard touchdown catch, ruling his hand hit out of bounds, and the Cowboys couldn't get into the end zone after the overturned reception.

"I couldn't quite believe they were able to hit a touchdown in that situation. I kind of kept looking for the replay," Manning said. "You know the game was not going to be over until that clock hit zero."

This was the 20th time in Manning's career that the Giants rallied in the fourth quarter to win. And this comeback came after New York blew an early 23-0 lead.

"It speaks about our resiliency. We know how to win these games," receiver Victor Cruz said. "We've been in a bunch of them."

After their sixth win in seven games since a season-opening home loss to Dallas, the Giants (6-2) hurriedly cleared out of Cowboys Stadium trying to get home as quickly as possible with Hurricane Sandy bearing down on the East Coast.

The Giants are 4-0 in Arlington since Jerry Jones' football palace opened in 2009 with a New York victory.

"I'm very disappointed right now," Jones said. "I thought after all that, our defense played well enough, our offense kept going and I thought we were going to get a chance to pull one out."

Coupled with Sunday losses by Philadelphia (3-4) and Washington (3-5), the Giants strengthened their hold on the NFC East lead halfway through their schedule.

New York led 23-0 just 2 minutes into the second quarter when defensive end Jason Pierre-Paul returned an interception 28 yards for a touchdown. That was the third of four interceptions thrown by Tony Romo, and Dallas (3-4) finished with six turnovers.

But the Giants didn't score again until Lawrence Tynes made a 43-yard field goal with 10:20 left for a 26-24 lead. He kicked a 37-yarder with 3? minutes remaining in the fourth for his fifth of the game.

Stevie Brown set up Tynes' last field goal with a fumble recovery and also had two interceptions.

"We have good leadership, good people," Giants coach Tom Coughlin said. "They're fighters in that locker room. ... Sometimes it comes out differently than it was designed."

Dallas got to the Giants 19 on one of its last drives. On fourth-and-1 with 1:03 left, Romo scrambled and was picked off by Brown.

After New York failed to get a first down on three running plays and Dallas used all three of its timeouts, the Cowboys got the ball back with 44 seconds left at the 30. They got to the Giants 37 before Bryant's catch between two defenders in the back of the end zone was overturned.

"We scratched and scraped," Giants defensive lineman Chris Canty said. "At the end, we still had to have a little luck to pull that one out."

Manning completed 15 of 29 passes for 192 yards with an interception.

Romo threw for a career-high 437 yards while completing 36 of 62 passes. Jason Witten broke his own Cowboys team record with 18 catches, which resulted in 167 yards. Miles Austin had nine catches for 133 yards and Bryant had five catches for 110 yards.

The Giants led 13-0 in the first quarter after Romo's first two interceptions.

Brown, who has five interceptions in six games, stepped in front of Bryant and had a 37-yard return to set up Tynes' 37-yard kick that made it 6-0. Three plays later, Corey Webster's 37-yard interception return led to Andre Brown's 1-yard TD.

Michael Coe recovered at the Dallas 15 when Bryant fumbled after fielding a punt over his head, setting up a 26-yard field goal.

Three plays later, Pierre-Paul broke off a block and jumped to grab the ball. He punctuated his first-ever pick and touchdown by dunking the ball over the crossbar.

Things were so bad then that Jones was booed when he came on the videoboard during a public service announcement about breast cancer awareness. On another unrelated video during that same timeout, coach Jason Garrett got the same treatment when his image appeared on the screen.

"I've been to boo school so to speak," Jones said. "Seriously. I'm sure the fans had the same feeling I did. I was frustrated, mad and knew that we had dug ourselves a hole that was going to take super effort to get out of."

Dallas scored the last 10 points of the half, then added two more touchdowns in the third quarter to go ahead. Romo faked a handoff and rolled right for a 1-yard score on fourth down, ending the play with an emphatic spike.

After the Giants went three-and-out, the Cowboys drove to the 1 again. Romo faked another handoff and started rolling right, when he then shuffled the ball ahead to John Phillips for a 1-yard pass that put Dallas up 24-23.

None of that mattered after the closing sequence.

"Just tough when you think you've won the game," Romo said. "It switches as that moment. You put a lot into it, obviously. We put a week's worth (of emotion) in that one game.

NOTES: The only Cowboys with more passing yards in a game are Don Meredith (460 in November 1963) and Troy Aikman (455 in November 1998). ... The only other time Dallas had three 100-yard receivers was Nov. 10, 1963, at San Francisco. ... Tynes is now the second-leading scorer in Giants history. His 17 points Sunday pushed his career total to 535 (113 field goals, 196 extra points). He passed Brad Daluiso's 526 points. The career leader is Pete Gogolak's 646.

___

Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-10-28-Giants-Cowboys/id-800bcad3cd8a454fb0befe4decf8d09c

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Monday, October 29, 2012

Biomarkers of behavior, therapeutic targets for adult B-acute lymphoblastic leukemia identified

Monday, October 29, 2012

New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.

The research, conducted by Ari Melnick, M.D., associate professor of medicine and director of the Raymond and Beverly Sackler Center for Biomedical and Physical Sciences at Weill Cornell Medical College and a hematologist-oncologist at New York-Presbyterian Hospital/Weill Cornell Medical Center, and colleagues, was published in Cancer Discovery, a journal of the American Association for Cancer Research.

Although B-acute lymphoblastic leukemia is highly curable in children, the disease is usually fatal in adults, and researchers have yet to identify why this is the case. Part of the explanation for the poorer outcomes in adults is the higher frequency of genetic alterations associated with unfavorable prognosis.

In order to better understand why these genetic alterations are associated with poor outcomes, Melnick and colleagues studied 215 diagnostic specimens obtained from adults with B-acute lymphoblastic leukemia who were participating in a large Eastern Cooperative Oncology Group phase III clinical trial.

"We performed an integrative epigenomics study to decode the instructions that determine how these cells behave," Melnick said. "The hope was that this would allow us to identify better survival biomarkers and new therapeutic targets."

In many cancers, genetic alterations work in conjunction with epigenetic changes (changes in the way that DNA is modified and packaged) to promote cancerous behaviors. Looking at the B-acute lymphoblastic leukemia specimens, Melnick and colleagues found that many of the leukemias' bad traits were a result of changes in the epigenetic code. In many cases, the epigenetic changes were directly linked to the proteins generated from the genetic alterations and could be used to identify key master regulators required for the leukemic cells to live, according to Melnick.

"For example, we found that a cell surface molecule called CD25 was an extremely powerful indicator of the presence of the most aggressive and fatal cases," Melnick said.

The researchers also discovered that abnormal forms of the E2A and MLL proteins occurring in B-acute lymphoblastic leukemias directly reprogram epigenetic settings at their binding sites throughout the genome.

Most notably, the researchers found that mutant forms of MLL epigenetically reprogramed leukemia cells to express the powerful oncoprotein BCL6, and that BCL6 was required to maintain the proliferation and survival of the leukemia cells.

"We then designed inhibitors of BCL6 and showed that we could kill leukemia cells from patients enrolled in the clinical trial by blocking its function," Melnick said.

Based on these results, the researchers plan to use CD25 as a biomarker to identify those patients who have the worst disease in the next set of clinical trials, and to tailor treatment appropriately. In addition, BCL6 inhibitors are currently being translated for use in humans, and they hope to develop clinical trials targeting BCL6 in MLL-rearranged leukemias.

"These results will ultimately lead to biomarkers that help guide treatment and to the development of therapies that will be more effective for patients with this aggressive form of leukemia," Melnick said.

###

American Association for Cancer Research: http://www.aacr.org

Thanks to American Association for Cancer Research for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/124889/Biomarkers_of_behavior__therapeutic_targets_for_adult_B_acute_lymphoblastic_leukemia_identified

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Gorilla grandma celebrates 55th birthday

By Monica Garske

Tammy Spratt / San Diego Zoo Safari Park via AP

Vila turns 55 this weekend and who keepers say is the third-oldest known western lowland gorilla in the world.

The third-oldest known gorilla in the world is celebrating her 55th birthday this weekend at the San Diego Zoo Safari Park, zoo officials announced.

While the hand-raised, western lowland gorilla named ?Vila? may be turning the big 55, zookeepers said she?s in remarkable condition for her age.

They credit the Southern California climate for Vila?s good health.

According to zoo officials, Vila has served as a surrogate mother to seven gorillas during her life and also plays grandmother to the San Diego Zoo?s youngest gorilla, Monroe.

View complete coverage at NBCSanDiego.com

On Friday morning Vila showed off her grandma skills by letting Monroe ride around on her back, as pictured above.

Besides her notable age and contributions as a surrogate mother, zoo officials said Vila has also made significant contributions to the understanding of her critically endangered species over the years.

She participated in a six-year study on great ape intelligence, which zoo officials said contributed to the base of scientific knowledge that researchers now have about gorillas.

Source: http://usnews.nbcnews.com/_news/2012/10/27/14750726-gorilla-grandma-celebrates-55th-birthday?lite

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Kris Jenner on Kanye West: Part of the Family!

Source: http://www.thehollywoodgossip.com/2012/10/kris-jenner-on-kanye-west-part-of-the-family/

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Andrew Sullivan: Romney 'Like an Alien That Ripped Off His Mask' at Debates

The Daily Beast's Andrew Sullivan blasted Republican presidential nominee Mitt Romney as a "brand new candidate" following this month's presidential debates, saying on the "This Week" roundtable that Romney "was like an alien that ripped off his mask" at the first debate.

"The big elephant in the room is that the Mitt Romney that showed up on October 3rd was like an alien that ripped off his mask and said, 'I'm brand new now,'" said Sullivan, editor of "The Dish" at The Daily Beast. "He has evolutionary ideology, like he still has evolving doctrines."

Sullivan, a self-identified conservative who supports President Obama and has criticized Romney regularly, called Romney a candidate who "has no core at all and has changed it a dozen times to appeal to whatever market share he's appealing to."

"I'm sorry, but Romney was a severe conservative from January to October, and now he's a new candidate," Sullivan said. "What I'm amazed at is why Republicans aren't scared about what he'll be in January or July."

Republican strategist and ABC News political analyst Nicolle Wallace rebutted that "whatever it is, is better than Obama," prompting Sullivan to question Romney's budget plans as "a massive increase in debt."

Gwen Ifill, moderator and managing editor of PBS' "Washington Week" said that Romney's debate performances helped him close the enthusiasm gap that has long plagued him among Republicans.

"At this point in the campaign, all that matters is who's got the last-minute enthusiasm," Ifill said. "You cannot argue that the Republicans, who had gotten a little depressed, were enthused after what they saw in that debate? Ask people who won all three of those debates, they said that the president won the last two, Romney won the first one, but Romney won all three. That's how important that first one [was]."

Like "This Week" on Facebook here. You can also follow the show on Twitter here.

Get more pure politics at ABC News.com/Politics and a lighter take on the news at OTUSNews.com

Israel kills Palestinian militant in Gaza: Palestinian officials

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Source: http://news.yahoo.com/israel-kills-palestinian-militant-gaza-palestinian-officials-000751385.htmlbruins boston bruins carl crawford mad cow disease rampart jimmy fallon jimmy fallon

Labrinth, Taylor Swift top UK music charts

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